To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. Am J Dent. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds Indian J Dent Sci. Tandkrmen har ett slipmedel som ger en mild polering och tar bort yttre flckar och fluor skyddar tnderna mot karies. The clinical significance of this study can be highlighted by the fact that this was a person-centred clinical trial where patients were the prime focus where thepatients suffering from DH. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. Docimo R et al. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. California Privacy Statement, Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. Product Details Characteristics and Benefits Characteristics: Unique Pro-Argin TM/MC technology based on natural process of tubule occlusion These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. Aust Dent J. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Statistical Package for the Social Sciences software v.21.0. When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Read our disclaimer for details. In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Pro-Argin technology helps to seal and repair . OTC dentifrices with Pro-argin and strontium acetate are effective for immediate pain relief from DH, and FCPS could be the best possible treatment option for long term management of DH. Cite this article. Article The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. Poster #3406, July 2018 IADR. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. 2017;59(4):4618. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief and Ayad et al. 75 ml. 6 Ipsos, Romania Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2-week trial, 545 respondents, 2015. Sealed channels protect against pain caused by hot, cold and sweet stimuli. J Clin Dent. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. Free postage. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. The benefits are backed by over a decade of clinical research, summarized as follows. Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. Lasting relief with 2x daily continued brushing. Colgate* Sensitive Pro-Relief TM/MC Toothpaste with Pro-Argin TM/MC Technology is the first toothpaste that is clinically proven to provide instant & lasting relief from dentin hypersensitivity. Fordeler Colgate SENSITIVE INSTANT Relief tannkrem er klinisk dokumentert virke i lpet av sekunder samtidig som den beskytter tannen mot at smerten skal komme tilbake. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. Compend Contin Educ Dent. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. Provided by the Springer Nature SharedIt content-sharing initiative. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. J Dent. This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. 2018. The limitation of our study is that fluoridated dentifrice was used as a control which, although regarded as not possessing any desensitising effects. Saba Arshad. J Clin Dent. Dentin hypersensitivity can have significant detrimental effects on your patients wellbeing and quality of life. volume21, Articlenumber:498 (2021) This binds to the negatively charged dentine surface like a magnet. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. Colgate Sensitive Pro-Relief Enamel Repair Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Last updated on May 11, 2021. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). All rights reserved. Department of Oral Biology, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS), Dow University of Health Sciences, Karachi, Pakistan, Department of Oral Biology, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan, Department of Research, School of Public Health, Dow University of Health Sciences, Karachi, Pakistan, You can also search for this author in All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. Participants were asked to pick up the envelope from the box. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Product Details Page . For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Anvnd tv gnger dagligen. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. 1997;24(11):80813. p values of<0.05 were considered as statistically significant. J Evid Based Dent Pract. . It is clinically proven for instant and lasting Sensitivity relief* How does it work? They don't. # In-vitro study, actual confocal images after 5 treatments. IRB-1351/DUHS/Approval/2019/184. CONSORT flow chart. 1). Docimo et al. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. However, there was no significant treatment difference between dentifrices containing Pro-argin and strontium acetate (p>0.05) at each efficacy interval. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. Book This toothpaste really does not help at all with symptoms of sensitive teeth. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. 1. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Privacy J Clin Dent 2009; 20 (Spec Iss): 123-130. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. Plus it has the freshness you trust from Colgate! [16] in a systematic review in 2015. Builds a protective barrier that acts like . Colgate Tandpasta Sensitive Instant Relief Whitening. Colgate-Palmolive Company 2018. 2 Docimo et al. In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. 2015;28(1):404. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. 2009;22:3A-7A. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. Colgate Sensitive Instant Relief Toothpaste starts blocking sensitivity pain instantly*. Another . Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. Ashwini S, Swatika K, Kamala DN. PubMed Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. Difference in effectiveness between strontium acetate and arginine-based toothpastes to relieve dentin hypersensitivity. (US). How to use This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. Pessoa OF, Loretto SC, Maia LC. J Dent. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. How does Colgate Sensitive Pro-Relief Repair & Prevent work? * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back
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